Omnicell / Tissue model specifications

Tendon

Assess inflammation, tenogenesis, matrix remodeling and local therapeutic delivery in engineered tendon systems.

Enquire about Tendon View specifications

01 / Model configurations

Inside the model.

Available systems

Perfused 3D fibrin hydrogel with healthy or tendinopathic human tendon stem/progenitor cells (hTSPCs)
Bioprinted ColMA with PLGA nanoparticles for fibrosis and chronic inflammation
Bioprinted GelMA with microfluidic-fabricated nanocarriers under dynamic perfusion for tendon–bone enthesis studies

Biological architecture

Healthy and inflammatory/diseased configurations; structured extracellular matrix and tendon–bone interfaces.

02 / Readouts

Endpoints & characterization

Tenogenic markers SCX and TNMD
Matrix markers COL1A1 and COL3A1
Inflammatory biomarkers IL-6 and IL-8
Collagen production, organization and remodeling
Tissue mechanics and matrix calcification
Local delivery, controlled release and tissue response

03 / Study applications

Testing options

Anti-inflammatory efficacy
Disease-modifying activity in tendinopathy
Tenogenic differentiation and regeneration
Anti-fibrotic testing
Nanomedicine screening and enthesis regeneration

Plan your model configuration

Cell sources, donor selection, tissue dimensions, culture duration, exposure schedule and assay acceptance criteria are defined for the selected study. The catalogue does not specify universal values for these parameters.

Model systems and testing options summarized from the September 2026 preclinical NAMs catalogue, page 10. Discuss availability and the endpoints required for your candidate with MAKBY.

Open tissue catalogue Discuss this model