MakbyAvailable systems
- Malignant melanoma
- Lung adenocarcinoma
- Colon cancer
- Breast cancer
Omnicell / Tissue model specifications
Immuno-oncology
Investigate efficacy, resistance, immune infiltration and treatment combinations in 3D human tumor–microenvironment models.
01 / Model configurations
Inside the model.
Biological architecture
Modular tumor-only, tumor–stroma, tumor–immune and multicellular configurations. Options include fibroblasts, endothelial and immune cells, basal-membrane invasion and bioreactor-enhanced growth.
Endpoints & characterization
- Tumor growth inhibition and cytostatic activity
- Checkpoint inhibitor response
- Drug recovery and regrowth
- Treatment sequencing
- Immune infiltration, tumor penetration and tumor-cell killing
- Stromal/vascular effects and treatment resistance
Testing options
- Checkpoint inhibitors and bispecific antibodies
- CAR-T, CAR-NK and other cell therapies
- Targeted treatments and combination strategies
- Comparison of tumor-only and multicellular models
Plan your model configuration
Cell sources, donor selection, tissue dimensions, culture duration, exposure schedule and assay acceptance criteria are defined for the selected study. The catalogue does not specify universal values for these parameters.
Model systems and testing options summarized from the September 2026 preclinical NAMs catalogue, page 7. Discuss availability and the endpoints required for your candidate with MAKBY.