MakbyAvailable systems
- Caco-2 models
- Primary intestinal organoids
- Primary-cell Transwell®-like models
- Primary co-cultures incorporating immune, endothelial or enteric neural cells
Omnicell / Tissue model specifications
Gastrointestinal
Investigate intestinal absorption, metabolism, transport and toxicity with a tiered model portfolio.
01 / Model configurations
Inside the model.
Biological architecture
Epithelial monocultures and multicellular intestinal systems; primary models can retain donor- and region-associated characteristics.
Endpoints & characterization
- Absorption, permeability, bioavailability and metabolism
- TEER and paracellular marker flux
- Cellular integrity and epithelial injury
- Histomorphometry and ultrastructure
- Tissue morphology and barrier disruption
Testing options
- Drug absorption and transport
- Intestinal metabolism
- Drug-induced GI toxicity
- Barrier-function studies
- Disease-specific and donor/segment-specific responses
- Custom tests for drugs, nutrients, nanoparticles and pathogens
Plan your model configuration
Cell sources, donor selection, tissue dimensions, culture duration, exposure schedule and assay acceptance criteria are defined for the selected study. The catalogue does not specify universal values for these parameters.
Model systems and testing options summarized from the September 2026 preclinical NAMs catalogue, page 6. Discuss availability and the endpoints required for your candidate with MAKBY.