Omnicell / Tissue model specifications

Oral mucosa

Characterize drug–mucosa interactions, local safety and transmucosal delivery.

01 / Model configurations

Inside the model.

Available systems

  • Reconstructed epidermal oral mucosal models
  • Primary-cell or cell-line systems
  • Co-culture models
  • Disease-specific configurations

Biological architecture

Reconstructed tissue and co-cultures for epithelial, stromal, immune or microbial interactions, depending on the project.

02 / Readouts

Endpoints & characterization

  • Epithelial viability and tissue damage
  • Barrier integrity and inflammatory responses
  • Permeability, flux, lag time and tissue retention
  • Drug transport and mucosal toxicity in the same system
03 / Study applications

Testing options

  • Biocompatibility and oral healthcare products
  • Buccal and sublingual drug delivery
  • Acute and repeated exposure
  • Mucositis, infection and inflammatory disease models
  • Patient-derived oral squamous-cell carcinoma response and comparison with normal mucosa, where configured

Plan your model configuration

Cell sources, donor selection, tissue dimensions, culture duration, exposure schedule and assay acceptance criteria are defined for the selected study. The catalogue does not specify universal values for these parameters.

Model systems and testing options summarized from the September 2026 preclinical NAMs catalogue, page 8. Discuss availability and the endpoints required for your candidate with MAKBY.