MakbyAvailable systems
- Human nasal mucosa (HNEC)
- Tracheo-bronchial mucosa (HTEC)
- Patient-derived COPD models
Omnicell / Tissue model specifications
Respiratory
Study airway function, local tolerability and disease-relevant pharmacological responses in human respiratory models.
01 / Model configurations
Inside the model.
Biological architecture
Primary epithelial air–liquid interface (ALI) models with differentiated, ciliated and secretory cells, mucus and innate immune responses.
Endpoints & characterization
- Histology and ultrastructure
- Ciliary beating and mucociliary transport
- Epithelial barrier integrity and permeability
- Mucin secretion and mucus production
- Cytokines, chemokines and epithelial repair
Testing options
- Anti-inflammatory and antiviral effects
- Mechanism of action and dose–response
- Local tolerability, infection and host response
- Nasal and inhaled formulations
- Small molecules, biologics, peptides, oligonucleotides and combination therapies
Plan your model configuration
Cell sources, donor selection, tissue dimensions, culture duration, exposure schedule and assay acceptance criteria are defined for the selected study. The catalogue does not specify universal values for these parameters.
Model systems and testing options summarized from the September 2026 preclinical NAMs catalogue, page 4. Discuss availability and the endpoints required for your candidate with MAKBY.